Addison’s disease statistics

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An “Addisonian crisis” or “adrenal crisis” is a constellation of symptoms that indicate severe adrenal insufficiency. This may be the result of either previously undiagnosed Addison’s disease, a disease process suddenly affecting adrenal function (such as adrenal hemorrhage), or an intercurrent problem (e.g. infection, trauma) in someone known to have Addison’s disease.
A review of a patient’s medical history based on the symptoms, especially the dark tanning of the skin, will lead a doctor to suspect addison’s disease.
Rarely, it may be due to a genetic abnormality of the adrenal glands. In children, about 70% of cases are caused by a congenital disease termed congenital adrenal hyperplasia, while 30% of the time adrenal damage is due to autoimmune disease, another inherited disease termed adrenoleukodystrophy, or less common causes.